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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a26ee446d48b3e1e5f66c54107b9576ab3ab2ecf886072e612a9d5706a74d111' 
  AND token = 'Yit9ILwL9/SOEBSXUGzjvV9OxVNBrMlVMGVkMSR6/qs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}