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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e63ad8dd525dc964e0b23deeec72b97f1b01ea3b6be83a002e6f3ab550b618c8' 
  AND token = '0+iVR5r0SiK5Iz1XRzaWxTBJJz6LAwhe7JctDZE1nZY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}