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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b61b33dfcdb1b2b040a230421ae83ab103ce2d9efe68b8a47da18d83602eb3d' 
  AND token = 'vD0w0fZlxEbY76JnNV0WSlTJmWCiDI+JUnFeNT7Wofw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}