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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '65941fd3045703ddb4e935802d93ded467269105c053cc0e7969f883d605b01b' 
  AND token = 'mGpwMI/xT3IQzwL7+R8xZjA+I1ZpMKs3xG3BFO6sMkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}