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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ecd2ffd504c999b336eee766f7d1d793859010ae56d6f8e52cac7a87a1fc590' 
  AND token = 'DH823wEEKIU8hRLCELR2cvJ2tGVUpsulAmBAEKo8hb8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}