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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41c115800070078acadc7eba855a09014685d2bf44cc74a9b86b646fc6fbc153' 
  AND token = 'UyWxHv+Fx2WhUDWrIRhjRDdfVc4JjU5mIYHnXY1iC8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}