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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859b3060f7e1bedbf5e72ba3a55f1032c142b2fbf259dbeef340c866e9d1915d' 
  AND token = 'NC+mz+p5R6B87svBygTbfj/6GRvtE5IDuY6ER5J8DEw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}