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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f721d564b1e23be0d7c9bec86a0e99b651832eff8c418d580c39f4d8ea9e7942' 
  AND token = '/M1FGal9IinlCNBtEb4IHvGrqB5ObnKmRCaiaLT1pJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}