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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd747b2b0c25cc7b5a0d0268b6d47a38974b26f978575ed1ba086465804ca87ce' 
  AND token = '+4if+tLyO+WRUKkDaHqqJnGD1fPsvmwDBXXdaZXIR34=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}