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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a0e021f8e9dcc62566923a624e4d2dfdceca626cfd590797668273ac378bdb4' 
  AND token = 'wQMgamfsrvh/gjy+dCUNHLtQLyiYa7GhXuaRxTcZLoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}