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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4805d6f571835369e30b36fb24ad7624be0a3e5d070b74a571579cdf827423d9' 
  AND token = 'Vzu+/q/5C05gHPAbz44qW2ow4n0Ahld7FYa8ig/olMg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}