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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0d87af49c3b352fa99b61bb79e80472c6362c59133a6a06bb005f9cfde3e6a67' 
  AND token = '0CCZtq0Hx7Mdizb2AeqHKqHpb0Q8GiYHAOWz1yQrVo0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}