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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e668eb15a2df7850fa4f1c1d726db047d424e185af97f3aeafd16f95870d364' 
  AND token = 'djDUVtA+15lATeMyJ/J8KavU0XTrNAtwgiFY0DvrWrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}