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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72c7dede1b86c3d22aeeac2a7990c33d64793c889ba56f7fdc504c6abea215dd' 
  AND token = 'KZ1WgEGQJkd7DOPDo2fz9F1Sh9Yd5/GlT8h7kptPXnk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}