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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed086dfa3f692db87dff3986ffac2de5afc8448aea660e81efe3fffd0ec4b701' 
  AND token = 'VI6HJzhl2IeD2Dcbib0yPuXuSPxLUXFjB2QjPjkm5Ww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}