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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c568c7b68131242bbb82b26180f143c7e09ad6a2fa35a215aeb59c042f7b669' 
  AND token = 'oIdLDKrPdOrFJA2Fke/q15K9/9U4/zd0O9YWYPSLmtk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}