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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '452b6fa896cb25676c00d34b8711d2366ebf8a8851527a3b938158a2cec6ae93' 
  AND token = 'IMXEFboaP+f8zrdyu14hjTAgGNRXML6cLfqOC5jjUgE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}