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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfa5309bae249364ab1fbaffa9264f826c52dd0cfc44c2d93a55a96fb3c61c54' 
  AND token = 'JVb6J7aaGdQaJo2hPRSYCwmMdb3lVn8cS5JgovX0CfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}