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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '250b8c21ab7c73d5cf04d4c6b577879eba789ef2e49332b74e6e719189cbf9a6' 
  AND token = 'mQHj4KW3bhOfRWHDuPqOx297X6VT63Xf51lyp4PBvok=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}