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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12bef5edda0df967e8f16ec536deb0752fc0e208e40df58d469416f7da27c9bc' 
  AND token = 'AIo/EZDI5VWlIe3C73j53ufMfxmG7mJ9WmzdjW9puRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}