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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '614e9285fe2eedd79a468c6db2ffe77260a4fbc1246d3e4322a611832eb7ea06' 
  AND token = 'IuavkMNR0uhW1OL7ik2rfwgDRBtH3DWoSQtX3Gaiwuw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}