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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e8318557a3f5020d102b037835b83f8f4800d340e9ea0b32f6d5cfbd9decb18' 
  AND token = 'NR8JPfSdnoX0JjRgHPazPs8teZY59iC6M6dGKWCgD4Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}