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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f03fed31f0e7b6a3bb646af2846d36ff6f534271ee448978a91b831cd939bb02' 
  AND token = 'UzV+lUeXDCKLlAMdG9NRaDsGs/xdptSPL4Ng57+7Dg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}