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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4967c8f01f71d498b883fb1a16821c293e9a83d651b8daff90a5ff3328b34f5' 
  AND token = 'eV19YBbn/fdmDxsZHoitr53tG9VP4IS3+91jYIJBU+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}