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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64a4103183b0d9925a1eb6bf42a0b2dd4497b18773211a06998b9b10d2282103' 
  AND token = 'OFYBDQHnV7oQOdozObuZ8zLsd+/wKdGfev111MRui8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00050

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}