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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '209d41eba6611a8199aee39eb288873cbc4014fbb36efb098c612e328b3939d8' 
  AND token = 'wF1ozDUZW/qj1CRR2Hysi3iz5fwXjmXQmyT4r8L+rn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}