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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8c01c849998d8bf197a1c395d17d004fcbdc983dd67f23f4c291df3787195e0' 
  AND token = 'ZyWYv2zh77SJ8EZXf1ggXKyuUzCv/4W1C9xd5VNzxNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}