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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5fdef4393c0b6e24ca84ffee45fd45792f9c677e7c8b18c8ebf3d22d114268b3' 
  AND token = 'o21QDOjzPE8l0935PhMnqfEoFngw4u3yiDc5lXgu27I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}