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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf3f66ad12218e0a1df75e9e1c32215ccee2dd0f64daad64e9f9f78941ecfeb8' 
  AND token = 'Ap3WpAff1Q4FYGR8mw1ARcCGBeRs5S8WlsZybOxUcRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}