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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cf5fdc55f6893c1d2be5f287b3e03453f664bf206270193009c086c50b3c71a' 
  AND token = 'u2ngsApSY31rTj82YaWDl77I/CMC/vqLvsNubIawcXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}