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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25369a7e11d5b83ef651a91e53d88f7b70fd6b2a8c3ba44f5a4a03f6c08bcbb6' 
  AND token = 'fjuFUF5rdI9TX0TmhYdgjT3xGuXCHmnPsjKc2ssPbVI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}