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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '997c89333bf36e3907950192010d088f31e0a30b857c9ff75cfba575a786f312' 
  AND token = 'yWSQXIs5XZ0sTUdtAkEm5KPEsIGwTBMPsui+YTZnK2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}