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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e6f7b7cd5666fd3ce0de86aa839c0a2e122153a95f9c443d6eed18fdba260312' 
  AND token = 'QeblM/bhaiAYZ7xvEI019H++nL21YFIdlehNIvHzQzs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}