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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd9b8188d63e9e51e1e2e0965594c4211f4f17334935fe69bf6a231e1c8145e3f' 
  AND token = 's0Ij+vJcSesZQnXwKJDlsi8DLXam1ICW7NKFGmhXkG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}