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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8ffd32e1b6144b8dab2bfb0a10df8e0c0c024187fd6f50a81378911f640a126' 
  AND token = 'se+jA5YRp+7M3Pq9StM2uETz4TKYvrhMunkXZblv9pA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}