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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afc4c4a33a8d6fd4852c585ef0fa51bbde26202245cc60a9b962d318d4a79927' 
  AND token = 't78fw9moAgos8vqDw+rXmXzmPJ6otv40Foilrd4x1oQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}