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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcf0ea027531cb7faa985599ecbf65dcd078a93ec61120a6409eb44e5afab1d' 
  AND token = 'v6DX40nn1kQr3HRzWtw9EJTrAqPvZ7NAQT7o5FxNwEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}