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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00f5cb59fbc5a509a69b014455d1bac58b27d8d1c2d9bf64057add085ed0380c' 
  AND token = '+Ze22qBANzWQYrbIhQrOZaoUs2JTYQ+OQAdntPyvrVk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00053

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}