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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49681d5bc9bf5b4fb0326e4825aada3c548c0b3965f99011d317a961d9713983' 
  AND token = 'utXyq1pkHa6oZQx5gtjd2lwWILfE6zoIH8FJ6Aqw5RU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}