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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9395d655971890665d7bff87f31f7ac7aec8e821131218e11418c350fe635ec' 
  AND token = '/XSVu259iy3A4v+XIYUSTeA17DzCtfHOCTQGBfIbC1w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}