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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '486c8e5a34fff4253cda3e46aaa4790665cecbfccd41b9ff9deedb262e33bb3a' 
  AND token = 'evxeg0o26PI+1HQw/3t1H6IoDB5MMPBwLA8QwF2vMGs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}