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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a850747f4ad2ad4e47bc98786735f5bf0b1af725be3ef40b42d418dc0ea71fa' 
  AND token = '4rzwuCLe9iF0lorFLMLtBxaxZLVaM5tqrIbLV8bURVA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}