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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea12418efb7addd66a053f50650f04340999ed2f9a3be1f081b8441a84a1c05c' 
  AND token = 'fXcTPd74L9VDnyHTs4oqmOwHhT2QY18OI7+VS5hDWhs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}