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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c381ebf1754e00c7b938dc2b042e4ce23a8762abf31d8afd651c8e66b3bbfe1a' 
  AND token = 'KCVLMC1schoimAaJsTpVRPlEa9W9ET5Djx0eDv33eq8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}