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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '185aa9b0ac050261fc599710bb73498b44ccadde9faa1489cf3a86732a994941' 
  AND token = 'CMsIK0195xY95cyIoc9kpwVWWdi55DWMpgblSjKQRTc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}