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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '391b7b50e9c6ceba1e010c65e2055a0b5529f52629e8bc0c203a012698c0a17e' 
  AND token = 'dZ02cyeQM5KrMbAB9QbpMdesDp+GlIjyUhNvqvJ8ln4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}