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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef1ef22b4243b93204380bfb57bd77ae563a246225a4338e27269d6268c3276f' 
  AND token = '/XQMZcFRLLhh9R2X4e5hjY+K99AxeDB2aN7LmGQQZy8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}