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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7c3ca04c763453d231c3e93573aafd6a1b8f3ceeabb0327da08e4904949b7f6f' 
  AND token = '37DSDctT/e+9vODOrfG/qmC+z2T7Bfo04ru3Ujsyc8Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}