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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea3481eb39af9952547f4e2f242c33699e68f42e07a804cee69636aa1fbbcda' 
  AND token = 'a4iAdPhAagmFCce+djTetJwDxGmJPWpmD2COxnU3i40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}