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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82a5355fc021783952a0d79b023386b10597a6b51d6522a6c1e11f8aac1aa031' 
  AND token = 'sTwOdd//1DIwUYohYK2W3uhBrUvq57TaXcfSJs04tz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}